The University Hospital Federation IMPEC

The University Hospital Federation (FHU) IMPEC IMproving Emergency Care directed by Prof. Yonathan Freund is the first research federation in emergency medicine in France.

The aim is to federate the research of all the emergency structures in the Paris metropolitan area, by encouraging collaborations between hospitals, to enhance the attractiveness of research in a difficult environment and to increase the international visibility of French research in emergency medicine, to improve the practice of doctors and paramedical staff for a better care of patients, to increase the access to care of fragile populations, to promote precision medicine and to develop paramedical research are their priorities of research

Our News

31 March and 1 April 2022 – Villa Gaby – Marseille – France After the great success of the 2021……

Press release…

The University Hospital Federation (FHU) IMPEC IMproving Emergency Care, which aims to federate, encourage, develop and promote medical and paramedical……

First federation in emergency medicine in France

5 workpackages

Research at the FHU IMPEC is divided into 5 workpackages:

– Early therapy in the critically ill

– Healthcare acces and suboptimal care for fragile population

– Resource allocation and precision medicine

– Paramedical research

– Medical education, medical errors and human factors

Professor Tabassome Simon will coordinate the support provided by the URC Est and Professor Alexandre Mebazaa, director of the FHU Promice, will coordinate the support provided by INSERM (unit 942).

What is a FHU? 

The increasingly competitive international context, marked by the emergence of new health challenges, justifies a new impetus for translational and clinical research.

The creation of University Hospital Federations (FHU) by the AP-HP, INSERM, and universities aims to strengthen hospital-university-research unit relations in order to stimulate medical research and improve the quality of care, through a more rapid diffusion of innovations.

The objective of the FHU is to encourage joint projects between hospitals, universities, research units, industry, etc. and to strengthen their collaboration on medical themes leading to breakthrough innovations.

Thus, these new federation will contribute to the integration of care, teaching and research with a specific governance. The creation of the FHU has three main objectives:

Stimulate hospital-university relations in order to set up collaborative projects on cutting

edge themes Increase the visibility and identification of priority themes in research, teaching and care:

-To reinforce the visibility and attractiveness of the themes promoted by the 3 partners (AP-HP, Inserm, Universities), particularly with regard to clinicians, researchers or academics and industrial partners,

-To promote a continuum between basic research, clinical research, translational research and care. The aim is to accelerate the transfer of research results to the patient’s bedside, to promote excellence in care through early access to innovation,

-Strengthen the common culture between research and clinical activities,

-In the field of teaching and skills development: set up specific actions for and through research that involve the youngest (medical students, residents),

–Diversifying, targeting and optimising funding


In 2012 and 2013, the APHP, the research organisations and the universities approved 16 University Hospital Departments (DHU) for 5 years. This programme and the 16 DHUs were evaluated by the HCERES. The report was very positive and recommended that the experience be repeated. The DHUs have therefore been very structuring for hospital research.

In this context and because they have rapidly changed the research panorama, particularly in the field of health and life sciences, a new call for projects has been launched in 2019, open to DHU teams and to new teams.

As a result, 21 University Hospital Federations (FHU) have been labelled for 5 years. The name DHU has been replaced by FHU which better describes the objective of these projects to bring together and federate clinical and research teams.

Others FHUs

SEPSIS : Saclay and Paris Seine Nord Endeavour to PerSonalize Interventions for Sepsis
Project leader : Djillali ANNANE

NeuroVasc : University Hospital Federation – FHU NeuroVasc to improve clinical care, treatment and reserarch in neurovascular disorders
Project leader : Hugues CHABRIAT

CHILD : Reducing mortality and severe morbidity in the fist 3 years of life
Project leader : Martin CHALUMEAU

DDS-ParisNet : Dental Diseases Network in Paris
Project leader : Catherine CHAUSSAIN & Ariane BERDAL

PROTHEE : Prosthetic joint infectgions: Innovative strategies to overcome a medico-surgical challenge
Project leader : Anne-Claude CREMIEUX

SENEC : Understanding SENEsCence to improve life course health trajectory
Project leader : Geneviève DERUMEAUX

Hépatinov : Innovations in Hepatology
Project leader : Jean-Charles DUCLOS-VALLEE

I2-D2 : Early Identification of individual Trajectories in NeuroDevelopmental Disorders
Project leader : Pierre GRESSENS

TRUE : InnovaTive the Rapy for immUne disordErs
Project leader : Philippe GRIMBERT

PREVENT_HF : Predict & Prevent Heart Failure in Young Subjects
Project leader : Jean-Sébastien HULOT

PHENIX : Excellence network for therapeutics in neuromuscular disorders
Project leader : Pascal LAFORÊT

ADAPT : Addiction and Psychiatry Transformation with Precision Medecine
Project leader : Marion LEBOYER

APOLLO : Personalized medecine in chronic cardiovascular, respiratory, renal diseases and organ transplantation
Project leader : Carmen LEFAUCHEUR

CARE : Cancer and Autoimmune / inflammatory diseases Relationships
Project leader : Xavier MARIETTE

PROMICE : PRecision Medecine for a cOMphrehensIve CarE of Critically ill patients
Project leader : Alexandre MEBAZAA

MOSAIC : Multiscale Optimized Strategy of Artificial Intelligence-based Imaging Biomarkers in Digestive Cancer Applications in hepatocellular carcinomas and neuro-endocrine tumors
Project leader : Valérie PARADIS

PaCeMM : Paris Center for Microbiome Medecine
Project leader : Harry SOKOL

PREMA : Fighting Prematurity
Project leader : Vassilis TSATSARIS

MAMUTH : Maladies Musculo-Squetettiques et innovations Thérapeutiques
Project leader : B FONTAINE, R VIALLE

NOR-SUD : Network of Research in Substance Use Disorders
Project leader : Florence VORSPAN

Organization chart



Project leader FHU IMPEC
Workpackage leader “Resource allocation and precision medicine”

Pr Tabasomme SIMON


Coordinator of the East Parisian clinical research platform

Pr Alexandre MEBAZAA


INSERM 942 Director
Project leader FHU PROMICE



Workpackage leader « Early therapy in the critically ill »



Workpackage leader « Healthcare access and suboptimal care for fragile population »



Workpackage leader « Medical education, medical errors and human factors »



Workpackage leader « Paramedical research »



Project manager FHU IMPEC



Avicenne Hospital

Pr. Frederic Adnet
Dr. Anne-Laure Féral Pierssens


Beaujon Hospital

Dr. Matthieu Gay

Bichat Hospital
Pr. Enrique Casalino
Cochin Hospital
Dr. Jérome Bokobza Dr. Jenifer Truchot Mr. Olivier Picot
Georges-Pompidou Hospital
Dr. Florent Fémy Dr. Richard Chocron
Gonesse Hospital
Dr. Mustapha Youssef Mme. Sonia Iazazga
Lariboisière Hospital
Dr. Anthony Chauvin
Hospital Hospital
Dr. Alain Gil Mpela Mme. Lisbeth Dusserre-Telmon
Pitié-Salpétrière Hospital
Pr. Yonathan Freund
Saint Antoine Hospital
Dr. Youri Yordanov
Saint Denis Hospital
Dr. Mathias Wargon
Saint Joseph Hospital
Dr. Camille Gerlier
Saint Louis Hospital

Dr. Olivier Peyroni

Mme. Maud Anastassiou

Tenon Hospital

Dr. Hélène Goulet